Effectiveness of Nicotinamide Mononucleotide (NMN)

The world's elderly population has been gradually increasing, thus the need for anti-aging nutraceuticals to ensure longevity and improve age-related complications is also on the rise. Among the many anti-aging supplements, nicotinamide mononucleotide (NMN) has been receiving a lot of attention from consumers and the scientific community.

How it works

The mitochondrial decay that leads to aging can be reversed by increasing nicotinamide adenine dinucleotide (NAD + ) levels in the body.NMN is a precursor to NAD + and acts as an intermediate in NAD + biosynthesis, and dietary supplements of NMN have been found to increase NAD + levels in the body.NMN occurs naturally in a variety of plant and animal food sources. In addition, several studies have been conducted to investigate the potential of biotechnological production and purification of NMN from bacteria and yeast. Studies have shown that NMN is converted to NAD+ when it enters the human body and has certain efficacy and effects on human health, which is why specific nicotinamide mononucleotide supplements are marketed.

The efficacy of NMN

1、Relieve heart and brain tissue damage

NMN can protect brain nerves and promote vascular and nerve regeneration by activating Nampt-NAD+ defense system, which is a potential anti-stroke therapeutic drug as it has a better protective effect on brain hemorrhage and nerve damage caused by brain hemorrhage transformation; it can also protect heart and reduce infarct area by simulating the protective effect of IPC.

2、Improve physical dysfunction

By supplementing nicotinamide mononucleotide, NAD+ availability will be increased, thus increasing the rate of mitochondrial oxygen consumption promoting the fusion of mitochondria, reducing the tendency of fission, allowing mitochondria to produce longer mitochondria in the hippocampal subregion, thus improving the respiratory function of mitochondria, which can be used as a potential drug for the treatment of Alzheimer's disease, Parkinson's disease and vascular disorders.

3、Improve insomnia

Nicotinamide mononucleotide as a substance of human cell energy generation, can be supplemented to make the human biological clock back to normal and also to improve, because NAD+ is complementary to our biological clock, through exogenous intake of NAD+ precursor nicotinamide mononucleotide can regulate the disorder of sleep disorder among the biological clock to adjust normal.

4、Treatment of metabolic diseases

After experiments, nicotinamide mononucleotide can improve islet dysfunction in mice, reverse FRD and pro-inflammatory cytokine-mediated changes in the expression of genes encoding islet markers, reduce the expression of pro-inflammatory factors and restore insulin secretion. In other words, NMN can play a role in protecting and repairing islets by participating in and regulating the endocrine of the body; preventing and controlling metabolic diseases such as diabetes and obesity.

5、Delay aging

NMN prevents age-related gene expression changes in a tissue-specific manner and enhances the oxidative metabolism of mitochondria in skeletal muscle, mediating, at least in part, its anti-aging effects.

NMN is widely available in everyday foods, including vegetables such as cauliflower and cabbage, fruits such as avocados and tomatoes, and meats such as raw beef, and if you are concerned about not getting enough NMN in your daily life, you can contact ZANCHENG to purchase our other vitamin and dietary supplement products.